Renal tubular function in glycerol-induced acute renal failure
نویسندگان
چکیده
منابع مشابه
Cystone, a well-known herbal formulation improves renal function in rats with acute renal failure (ARF) induced by Glycerol intoxication
The present study was aimed to evaluate the beneficial effect of Cystone syrup in an experimental model of glycerol-induced acute renal failure (ARF) in rats. Biochemical parameters, kidney weight and histopathological evaluation were performed to conclude the beneficial effect of Cystone syrup. Administration of single dose of 50% v/v glycerol (8ml/kg.i.m) caused severe renal dysfunction assoc...
متن کاملTubular function in glycerol-induced acute renal failure in rats: effect of saline loading and prior acute renal failure.
1. Chronic saline loading and prior induction of acute renal failure are manoeuvres which have been reported to protect against the development of acute renal failure. The underlying mechanisms are unclear. The purpose of the present study was to examine the effect of these protective manoeuvres on glomerular filtration rate (GFR) and proximal and distal tubular function in the glycerol-induced...
متن کاملcystone, a well-known herbal formulation improves renal function in rats with acute renal failure (arf) induced by glycerol intoxication
the present study was aimed to evaluate the beneficial effect of cystone syrup in an experimental model of glycerol-induced acute renal failure (arf) in rats. biochemical parameters, kidney weight and histopathological evaluation were performed to conclude the beneficial effect of cystone syrup. administration of single dose of 50% v/v glycerol (8ml/kg.i.m) caused severe renal dysfunction assoc...
متن کاملPotential contribution of endothelin to renal abnormalities in glycerol-induced acute renal failure in rats.
We studied the possible participation of endothelin-1 (ET-1) in the pathogenesis of renal damage in glycerol-induced acute renal failure (ARF). Cortical mRNA expression of ET-1 increased, peaking at 10 hr postinjury, but this did not occur in the medulla, plasma concentration and urinary excretion of ET-1 also increased in this model. There was no change in ETA receptor mRNA, whereas the ETB re...
متن کاملCardiac output and renal blood flow in glycerol-induced acute renal failure in the rat.
Cardiac output (CO) and renal blood flow (RBF) were simultaneously evaluated by the microsphere method in water-drinking and chronic saline-drinking rats at 3, 12 and 24 hours after induction of acute renal failure by glycerol injection. Threee hours after glycerol injection CO and RBF decreased to 36% and 20% of the respective controls in water-drinking rats and to 41% and 24% of the controls ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1980
ISSN: 0085-2538
DOI: 10.1038/ki.1980.156